"Compression Devices Are an Effective Therapy for Restless Legs Syndrome" 2009

A Prospective, Randomized, Double-Blinded Controlled Study by Christopher J. Lettieri, MD, FCCP; and Arn H. Eliasson, MD, FCCP Background: Pharmacotherapy for restless legs syndrome (RLS) may be ineffective or complicated by side effects. Uncontrolled series using pneumatic compression devices (PCDs) have been shown to reduce symptoms of RLS. We sought to assess the efficacy of PCDs as a non-pharmacologic treatment for RLS. Conclusion: PCDs resulted in clinically significant improvements in symptoms of RLS in comparison to the use of sham devices and may be an effective adjunctive or alternative therapy for RLS. To download full text - Click Here

"Restless Legs Syndrome in Patients with Venous Disorders: an untold story" 2007

A prospective study profiling the profile of restless leg syndrome in patients presenting to a phlebology practice by B. McDonagh, MD, T King, MD, and R C Guptan, MD. Objective: To study the profiles of restless legs syndrome in patients with venous disorders. Conclusion: Restless Legs Syndrome appears to be a common overlapping clinical syndrome in patients with chronic venous disorders. To download full text - Click Here

"Effects of a Novel Venous-Return Assist Device (VENOWAVE) on the Lower Limb Venous Flow in Patients with Post-Thrombotic Syndrome" (PTS) 2002

A study by Martin O'Donnell, Jeff Ginsberg, John Saringer, Clive Kearon, Deborah Magier, Mary Kolich, Jim Julian, and Jack Hirsh at Henderson Research Centre and McMaster University. Objective: To determine if the VENOWAVE increases peak venous flow (PVF) in patients with PTS. Conclusion: The VENOWAVE increased PVF in patients with PTS and has the potential as a treatment for these conditions. To download full text - Click Here